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In silico identification of modulators of J domain protein-Hsp70 interactions in Plasmodium falciparum: a drug repurposing strategy against malaria

Plasmodium falciparum is a unicellular, intracellular protozoan parasite, and the causative agent of malaria in humans, a deadly vector borne infectious disease. A key phase of malaria pathology, is the invasion of human erythrocytes, resulting in drastic remodeling by exported parasite proteins, in...

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Detalles Bibliográficos
Autores principales: Singh, Harpreet, Almaazmi, Shaikha Y., Dutta, Tanima, Keyzers, Robert A., Blatch, Gregory L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445141/
https://www.ncbi.nlm.nih.gov/pubmed/37621993
http://dx.doi.org/10.3389/fmolb.2023.1158912