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LncRNA SNHG1 knockdown inhibits hyperglycemia induced ferroptosis via miR‐16‐5p/ACSL4 axis to alleviate diabetic nephropathy

BACKGROUND: Hyperglycemia accelerates the development of diabetic nephropathy (DN) by inducing renal tubular injury. Nevertheless, the mechanism has not been elaborated fully. Here, the pathogenesis of DN was investigated to seek novel treatment strategies. METHODS: A model of diabetic nephropathy w...

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Detalles Bibliográficos
Autores principales: Fang, Xiangdong, Song, Jianling, Chen, Yanxia, Zhu, Shuying, Tu, Weiping, Ke, Ben, Wu, Lidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445199/
https://www.ncbi.nlm.nih.gov/pubmed/37315165
http://dx.doi.org/10.1111/jdi.14036