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Blockade of glucagon increases muscle mass and alters fiber type composition in mice deficient in proglucagon‐derived peptides
AIMS/INTRODUCTION: Glucagon is secreted from pancreatic α‐cells and plays an important role in amino acid metabolism in liver. Various animal models deficient in glucagon action show hyper‐amino acidemia and α‐cell hyperplasia, indicating that glucagon contributes to feedback regulation between the...
Autores principales: | Ueno, Shinji, Seino, Yusuke, Hidaka, Shihomi, Nakatani, Masashi, Hitachi, Keisuke, Murao, Naoya, Maeda, Yasuhiro, Fujisawa, Haruki, Shibata, Megumi, Takayanagi, Takeshi, Iizuka, Katsumi, Yabe, Daisuke, Sugimura, Yoshihisa, Tsuchida, Kunihiro, Hayashi, Yoshitaka, Suzuki, Atsushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445200/ https://www.ncbi.nlm.nih.gov/pubmed/37300240 http://dx.doi.org/10.1111/jdi.14032 |
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