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Synthesis of Site-Specific Antibody–[60]Fullerene–Oligonucleotide Conjugates for Cellular Targeting
[Image: see text] An ideal therapeutic antibody–oligonucleotide conjugate (AOC) would be a uniform construct, contain a maximal oligonucleotide (ON) payload, and retain the antibody (Ab)-mediated binding properties, which leads to an efficient delivery of the ON cargo to the site of therapeutic acti...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445261/ https://www.ncbi.nlm.nih.gov/pubmed/37432881 http://dx.doi.org/10.1021/acsabm.3c00318 |