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Synthesis of Site-Specific Antibody–[60]Fullerene–Oligonucleotide Conjugates for Cellular Targeting

[Image: see text] An ideal therapeutic antibody–oligonucleotide conjugate (AOC) would be a uniform construct, contain a maximal oligonucleotide (ON) payload, and retain the antibody (Ab)-mediated binding properties, which leads to an efficient delivery of the ON cargo to the site of therapeutic acti...

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Detalles Bibliográficos
Autores principales: Äärelä, Antti, Räsänen, Kati, Holm, Patrik, Salo, Harri, Virta, Pasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445261/
https://www.ncbi.nlm.nih.gov/pubmed/37432881
http://dx.doi.org/10.1021/acsabm.3c00318