Boronate-Based Oxidant-Responsive Derivatives of Acetaminophen as Proinhibitors of Myeloperoxidase

[Image: see text] Myeloperoxidase (MPO) is an important component of the human innate immune system and the main source of a strong oxidizing and chlorinating species, hypochlorous acid (HOCl). Inadvertent, misplaced, or excessive generation of HOCl by MPO is associated with multiple human inflammat...

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Detalles Bibliográficos
Autores principales: Pierzchała, Karolina, Pięta, Jakub, Pięta, Marlena, Rola, Monika, Zielonka, Jacek, Sikora, Adam, Marcinek, Andrzej, Michalski, Radosław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445283/
https://www.ncbi.nlm.nih.gov/pubmed/37534491
http://dx.doi.org/10.1021/acs.chemrestox.3c00140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445283/
https://www.ncbi.nlm.nih.gov/pubmed/37534491
http://dx.doi.org/10.1021/acs.chemrestox.3c00140

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