Intratumoral T-cell and B-cell receptor architecture associates with distinct immune tumor microenvironment features and clinical outcomes of anti-PD-1/L1 immunotherapy

BACKGROUND: Effective cooperation between B-cells and T-cells within the tumor microenvironment may lead to the regression of established tumors. B-cells and T-cells can recognize tumor antigens with exquisite specificity via their receptor complexes. Nevertheless, whether a diverse intratumoral B-c...

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Detalles Bibliográficos
Autores principales: Schina, Aimilia, Sztupinszki, Zsofia, Marie Svane, Inge, Szallasi, Zoltan, Jönsson, Göran, Donia, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445359/
https://www.ncbi.nlm.nih.gov/pubmed/37604641
http://dx.doi.org/10.1136/jitc-2023-006941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445359/
https://www.ncbi.nlm.nih.gov/pubmed/37604641
http://dx.doi.org/10.1136/jitc-2023-006941

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