C1q(+) tumor-associated macrophages contribute to immunosuppression through fatty acid metabolic reprogramming in malignant pleural effusion

BACKGROUND: Although immune checkpoint blockade (ICB) therapy has shown remarkable benefits in cancers, a subset of patients with cancer exhibits unresponsiveness or develop acquired resistance due to the existence of abundant immunosuppressive cells. Tumor-associated macrophages (TAMs), as the domi...

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Detalles Bibliográficos
Autores principales: Zhang, Siyu, Peng, Wenbei, Wang, Haolei, Xiang, Xuan, Ye, Linlin, Wei, Xiaoshan, Wang, Zihao, Xue, Qianqian, Chen, Long, Su, Yuan, Zhou, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445384/
https://www.ncbi.nlm.nih.gov/pubmed/37604643
http://dx.doi.org/10.1136/jitc-2023-007441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445384/
https://www.ncbi.nlm.nih.gov/pubmed/37604643
http://dx.doi.org/10.1136/jitc-2023-007441

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