Cytomegalovirus cyclin-dependent kinase ortholog vCDK/pUL97 undergoes regulatory interaction with human cyclin H and CDK7 to codetermine viral replication efficiency

Human cytomegalovirus (HCMV) infection is shaped by a tightly regulated interplay between viral and cellular proteins. Distinct kinase activities, such as the viral cyclin-dependent kinase ortholog (vCDK) pUL97 and cellular CDK7 are both crucial for efficient viral replication. Previously, we report...

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Detalles Bibliográficos
Autores principales: Schütz, Martin, Wangen, Christina, Sommerer, Mona, Kögler, Melanie, Eickhoff, Jan, Degenhart, Carsten, Klebl, Bert, Naing, Zin, Egilmezer, Ece, Hamilton, Stuart T., Rawlinson, William D., Sticht, Heinrich, Marschall, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445456/
https://www.ncbi.nlm.nih.gov/pubmed/37591314
http://dx.doi.org/10.1016/j.virusres.2023.199200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445456/
https://www.ncbi.nlm.nih.gov/pubmed/37591314
http://dx.doi.org/10.1016/j.virusres.2023.199200

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