Development of a robust UPLC-MS/MS method for the quantification of riluzole in human plasma and its application in pharmacokinetics

Introduction: The aim of the present study was to establish a simple method for the determination of riluzole in human plasma by ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) and apply it for the determination of riluzole in amyotrophic lateral sclerosis (ALS) patients...

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Detalles Bibliográficos
Autores principales: Sun, Zhuo, Liu, Xin, Zuo, Wei, Fu, Qiang, Xu, Tingting, Cui, Liying, Zhang, Bo, Peng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445645/
https://www.ncbi.nlm.nih.gov/pubmed/37621312
http://dx.doi.org/10.3389/fphar.2023.1227354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445645/
https://www.ncbi.nlm.nih.gov/pubmed/37621312
http://dx.doi.org/10.3389/fphar.2023.1227354

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