Colocalization of corneal resistance factor GWAS loci with GTEx e/sQTLs highlights plausible candidate causal genes for keratoconus postnatal corneal stroma weakening

Background: Genome-wide association studies (GWAS) for corneal resistance factor (CRF) have identified 100s of loci and proved useful to uncover genetic determinants for keratoconus, a corneal ectasia of early-adulthood onset and common indication of corneal transplantation. In the current absence o...

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Detalles Bibliográficos
Autores principales: Jiang, Xinyi, Boutin, Thibaud, Vitart, Veronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445647/
https://www.ncbi.nlm.nih.gov/pubmed/37621707
http://dx.doi.org/10.3389/fgene.2023.1171217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445647/
https://www.ncbi.nlm.nih.gov/pubmed/37621707
http://dx.doi.org/10.3389/fgene.2023.1171217

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