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Combined anti-S1 and anti-S2 antibodies from hybrid immunity elicit potent cross-variant ADCC against SARS-CoV-2

Antibodies capable of neutralizing SARS-CoV-2 are well studied, but Fc receptor–dependent antibody activities that can also significantly impact the course of infection have not been studied in such depth. Since most SARS-CoV-2 vaccines induce only anti-spike antibodies, here we investigated spike-s...

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Detalles Bibliográficos
Autores principales: Grant, Michael D., Bentley, Kirsten, Fielding, Ceri A., Hatfield, Keeley M., Ings, Danielle P., Harnum, Debbie, Wang, Eddie C.Y., Stanton, Richard J., Holder, Kayla A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445686/
https://www.ncbi.nlm.nih.gov/pubmed/37338994
http://dx.doi.org/10.1172/jci.insight.170681