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α7nAChR activation in AT2 cells promotes alveolar regeneration through WNT7B signaling in acute lung injury

Reducing inflammatory damage and improving alveolar epithelium regeneration are two key approaches to promoting lung repair in acute lung injury/acute respiratory distress syndrome (ALI/ARDS). Stimulation of cholinergic α7 nicotinic acetylcholine receptor (α7nAChR, coded by Chrna7) signaling could d...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoyan, Zhang, Cuiping, Wei, Tianchang, Chen, Jie, Pan, Ting, Li, Miao, Wang, Lu, Song, Juan, Chen, Cuicui, Zhang, Yan, Song, Yuanlin, Su, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445688/
https://www.ncbi.nlm.nih.gov/pubmed/37410546
http://dx.doi.org/10.1172/jci.insight.162547