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Preferential killing of melanoma cells by a p16-related peptide

We report the identification of a synthetic, cell-penetrating peptide able to kill human melanoma cells efficiently and selectively, while being less toxic to normal human melanocytes and nontoxic to human fibroblasts. The peptide is based on the target-binding site of the melanoma suppressor and se...

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Detalles Bibliográficos
Autores principales: Soo, Julia K., Castle, Joanna T., Bennett, Dorothy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445694/
https://www.ncbi.nlm.nih.gov/pubmed/37522264
http://dx.doi.org/10.1242/bio.059965