Separation of transcriptional repressor and activator functions in Drosophila HDAC3

The histone deacetylase HDAC3 is associated with the NCoR/SMRT co-repressor complex, and its canonical function is in transcriptional repression, but it can also activate transcription. Here, we show that the repressor and activator functions of HDAC3 can be genetically separated in Drosophila. A ly...

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Detalles Bibliográficos
Autores principales: Tang, Min, Regadas, Isabel, Belikov, Sergey, Shilkova, Olga, Xu, Lei, Wernersson, Erik, Liu, Xuewen, Wu, Hongmei, Bienko, Magda, Mannervik, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445730/
https://www.ncbi.nlm.nih.gov/pubmed/37455638
http://dx.doi.org/10.1242/dev.201548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445730/
https://www.ncbi.nlm.nih.gov/pubmed/37455638
http://dx.doi.org/10.1242/dev.201548

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