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A TGF-β-responsive enhancer regulates SRC expression and epithelial–mesenchymal transition-associated cell migration

The non-receptor tyrosine kinase SRC is overexpressed and/or hyperactivated in various human cancers, and facilitates cancer progression by promoting invasion and metastasis. However, the mechanisms underlying SRC upregulation are poorly understood. In this study, we demonstrate that transforming gr...

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Detalles Bibliográficos
Autores principales: Noshita, Soshi, Kubo, Yuki, Kajiwara, Kentaro, Okuzaki, Daisuke, Nada, Shigeyuki, Okada, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445741/
https://www.ncbi.nlm.nih.gov/pubmed/37439249
http://dx.doi.org/10.1242/jcs.261001