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The endosomal system of primary human vascular endothelial cells and albumin–FcRn trafficking

Human serum albumin (HSA) has a long circulatory half-life owing, in part, to interaction with the neonatal Fc receptor (FcRn or FCGRT) in acidic endosomes and recycling of internalised albumin. Vascular endothelial and innate immune cells are considered the most relevant cells for FcRn-mediated alb...

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Detalles Bibliográficos
Autores principales: Pannek, Andreas, Becker-Gotot, Janine, Dower, Steven K., Verhagen, Anne M., Gleeson, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10445748/
https://www.ncbi.nlm.nih.gov/pubmed/37565427
http://dx.doi.org/10.1242/jcs.260912