Cargando…

Treponema pallidum promoted microglia apoptosis and prevented itself from clearing by human microglia via blocking autophagic flux

Treponema pallidum (Tp) has a well-known ability to evade the immune system and can cause neurosyphilis by invading the central nervous system (CNS). Microglia are resident macrophages of the CNS that are essential for host defense against pathogens, this study aims to investigate the interaction be...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Yun-Ting, Wu, Kai-Xuan, Wang, Xiao-Tong, Zhao, Yuan-Yi, Jiang, Xiao-Yong, Liu, Dan, Tong, Man-Li, Liu, Li-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446187/
https://www.ncbi.nlm.nih.gov/pubmed/37611054
http://dx.doi.org/10.1371/journal.ppat.1011594