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Treponema pallidum promoted microglia apoptosis and prevented itself from clearing by human microglia via blocking autophagic flux
Treponema pallidum (Tp) has a well-known ability to evade the immune system and can cause neurosyphilis by invading the central nervous system (CNS). Microglia are resident macrophages of the CNS that are essential for host defense against pathogens, this study aims to investigate the interaction be...
Autores principales: | Hu, Yun-Ting, Wu, Kai-Xuan, Wang, Xiao-Tong, Zhao, Yuan-Yi, Jiang, Xiao-Yong, Liu, Dan, Tong, Man-Li, Liu, Li-Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446187/ https://www.ncbi.nlm.nih.gov/pubmed/37611054 http://dx.doi.org/10.1371/journal.ppat.1011594 |
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