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The MGF300-2R protein of African swine fever virus is associated with viral pathogenicity by promoting the autophagic degradation of IKKα and IKKβ through the recruitment of TOLLIP

The multigene family genes (MGFs) in the left variable region (LVR) of the African swine fever virus (ASFV) genome have been reported to be involved in viral replication in primary porcine alveolar macrophages (PAMs) and virulence in pigs. However, the exact functions of key MGFs in the LVR that reg...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Luo, Rui, Zhang, Jing, Lu, Zhanhao, Li, Lian-Feng, Zheng, Yong-Hui, Pan, Li, Lan, Jing, Zhai, Huanjie, Huang, Shujian, Sun, Yuan, Qiu, Hua-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446188/
https://www.ncbi.nlm.nih.gov/pubmed/37566637
http://dx.doi.org/10.1371/journal.ppat.1011580