Amphiregulin couples IL1RL1(+) regulatory T cells and cancer-associated fibroblasts to impede antitumor immunity

Regulatory T (T(reg)) cells and cancer-associated fibroblasts (CAFs) jointly promote tumor immune tolerance and tumorigenesis. The molecular apparatus that drives T(reg) cell and CAF coordination in the tumor microenvironment (TME) remains elusive. Interleukin 33 (IL-33) has been shown to enhance fi...

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Detalles Bibliográficos
Autores principales: Sun, Runzi, Zhao, Hongyu, Gao, David Shihong, Ni, Andrew, Li, Haochen, Chen, Lujia, Lu, Xinghua, Chen, Kong, Lu, Binfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446484/
https://www.ncbi.nlm.nih.gov/pubmed/37611111
http://dx.doi.org/10.1126/sciadv.add7399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446484/
https://www.ncbi.nlm.nih.gov/pubmed/37611111
http://dx.doi.org/10.1126/sciadv.add7399

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