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Amphiregulin couples IL1RL1(+) regulatory T cells and cancer-associated fibroblasts to impede antitumor immunity

Regulatory T (T(reg)) cells and cancer-associated fibroblasts (CAFs) jointly promote tumor immune tolerance and tumorigenesis. The molecular apparatus that drives T(reg) cell and CAF coordination in the tumor microenvironment (TME) remains elusive. Interleukin 33 (IL-33) has been shown to enhance fi...

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Detalles Bibliográficos
Autores principales:	Sun, Runzi, Zhao, Hongyu, Gao, David Shihong, Ni, Andrew, Li, Haochen, Chen, Lujia, Lu, Xinghua, Chen, Kong, Lu, Binfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446484/ https://www.ncbi.nlm.nih.gov/pubmed/37611111 http://dx.doi.org/10.1126/sciadv.add7399

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