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FAM76B regulates NF-κB-mediated inflammatory pathway by influencing the translocation of hnRNPA2B1

FAM76B has been reported to be a nuclear speckle-localized protein with unknown function. In this study, FAM76B was first demonstrated to inhibit the NF-κB-mediated inflammatory pathway by affecting the translocation of hnRNPA2B1 in vitro. We further showed that FAM76B suppressed inflammation in viv...

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Detalles Bibliográficos
Autores principales: Wang, Dongyang, Zheng, Xiaojing, Chai, Lihong, Zhao, Junli, Zhu, Jiuling, Li, Yanqing, Yang, Peiyan, Mao, Qinwen, Xia, Haibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446823/
https://www.ncbi.nlm.nih.gov/pubmed/37643469
http://dx.doi.org/10.7554/eLife.85659