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In Silico Evaluation of Variant Calling Methods for Bacterial Whole-Genome Sequencing Assays
Identification and analysis of clinically relevant strains of bacteria increasingly relies on whole-genome sequencing. The downstream bioinformatics steps necessary for calling variants from short-read sequences are well-established but seldom validated against haploid genomes. We devised an in sili...
Autores principales: | Seah, Yee Mey, Stewart, Mary K., Hoogestraat, Daniel, Ryder, Molly, Cookson, Brad T., Salipante, Stephen J., Hoffman, Noah G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446864/ https://www.ncbi.nlm.nih.gov/pubmed/37428072 http://dx.doi.org/10.1128/jcm.01842-22 |
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