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Dysregulated cross-talk between alveolar epithelial cells and stromal cells in idiopathic pulmonary fibrosis reduces epithelial regenerative capacity

In idiopathic pulmonary fibrosis (IPF) constant epithelial micro-injury and aberrant interactions within the stromal micro-environment lead to abnormal alveolar repair and fibrosis. We hypothesized that alveolar epithelial regenerative responses in IPF are impaired due to disturbed crosstalk between...

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Detalles Bibliográficos
Autores principales: Wisman, Marissa, Nizamoglu, Mehmet, Noordhoek, Jacobien A., Timens, Wim, Burgess, Janette K., Heijink, Irene H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10446880/
https://www.ncbi.nlm.nih.gov/pubmed/37621459
http://dx.doi.org/10.3389/fmed.2023.1182368