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Brief early life angiotensin-converting enzyme inhibition attenuates the diuretic response to saline loading in sheep with solitary functioning kidney

A solitary functioning kidney (SFK) from birth predisposes to hypertension and kidney dysfunction, and this may be associated with impaired fluid and sodium homeostasis. Brief and early angiotensin-converting enzyme inhibition (ACEi) in a sheep model of SFK delays onset of kidney dysfunction. We hyp...

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Detalles Bibliográficos
Autores principales: McArdle, Zoe, Singh, Reetu R., Moritz, Karen M., Schreuder, Michiel F., Denton, Kate M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447225/
https://www.ncbi.nlm.nih.gov/pubmed/37565514
http://dx.doi.org/10.1042/CS20230663