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Tail engagement of arrestin at the glucagon receptor

Arrestins have pivotal roles in regulating G protein-coupled receptor (GPCR) signalling by desensitizing G protein activation and mediating receptor internalization(1,2). It has been proposed that the arrestin binds to the receptor in two different conformations, ‘tail’ and ‘core’, which were sugges...

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Detalles Bibliográficos
Autores principales: Chen, Kun, Zhang, Chenhui, Lin, Shuling, Yan, Xinyu, Cai, Heng, Yi, Cuiying, Ma, Limin, Chu, Xiaojing, Liu, Yuchen, Zhu, Ya, Han, Shuo, Zhao, Qiang, Wu, Beili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447241/
https://www.ncbi.nlm.nih.gov/pubmed/37558880
http://dx.doi.org/10.1038/s41586-023-06420-x