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Tail engagement of arrestin at the glucagon receptor
Arrestins have pivotal roles in regulating G protein-coupled receptor (GPCR) signalling by desensitizing G protein activation and mediating receptor internalization(1,2). It has been proposed that the arrestin binds to the receptor in two different conformations, ‘tail’ and ‘core’, which were sugges...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447241/ https://www.ncbi.nlm.nih.gov/pubmed/37558880 http://dx.doi.org/10.1038/s41586-023-06420-x |