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Single-cell analyses implicate ascites in remodeling the ecosystems of primary and metastatic tumors in ovarian cancer

Ovarian cancer (OC) is an aggressive gynecological tumor usually diagnosed with widespread metastases and ascites. Here, we depicted a single-cell landscape of the OC ecosystem with five tumor-relevant sites, including omentum metastasis and malignant ascites. Our data reveal the potential roles of...

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Detalles Bibliográficos
Autores principales: Zheng, Xiaocui, Wang, Xinjing, Cheng, Xi, Liu, Zhaoyuan, Yin, Yujia, Li, Xiaoduan, Huang, Zhihao, Wang, Ziliang, Guo, Wei, Ginhoux, Florent, Li, Ziyi, Zhang, Zemin, Wang, Xipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447252/
https://www.ncbi.nlm.nih.gov/pubmed/37488416
http://dx.doi.org/10.1038/s43018-023-00599-8