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Development of a LAG-3 immunohistochemistry assay for melanoma

AIMS: A robust immunohistochemistry (IHC) assay was developed to detect lymphocyte-activation gene 3 (LAG-3) expression by immune cells (ICs) in tumour tissues. LAG-3 is an immuno-oncology target with demonstrable clinical benefit, and there is a need for a standardised, well-characterised assay to...

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Detalles Bibliográficos
Autores principales: Johnson, Lori, McCune, Bryan, Locke, Darren, Hedvat, Cyrus, Wojcik, John B, Schroyer, Caitlin, Yan, Jim, Johnson, Krystal, Sanders-Cliette, Angela, Samala, Sujana, Dillon, Lloye M, Anderson, Steven, Shuster, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447394/
https://www.ncbi.nlm.nih.gov/pubmed/35534200
http://dx.doi.org/10.1136/jclinpath-2022-208254