Preclinical evaluation of manufacturable SARS-CoV-2 spike virus-like particles produced in Chinese Hamster Ovary cells

BACKGROUND: As the COVID-19 pandemic continues to evolve, novel vaccines need to be developed that are readily manufacturable and provide clinical efficacy against emerging SARS-CoV-2 variants. Virus-like particles (VLPs) presenting the spike antigen at their surface offer remarkable benefits over o...

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Detalles Bibliográficos
Autores principales: Alpuche-Lazcano, Sergio P., Stuible, Matthew, Akache, Bassel, Tran, Anh, Kelly, John, Hrapovic, Sabahudin, Robotham, Anna, Haqqani, Arsalan, Star, Alexandra, Renner, Tyler M., Blouin, Julie, Maltais, Jean-Sébastien, Cass, Brian, Cui, Kai, Cho, Jae-Young, Wang, Xinyu, Zoubchenok, Daria, Dudani, Renu, Duque, Diana, McCluskie, Michael J., Durocher, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447459/
https://www.ncbi.nlm.nih.gov/pubmed/37612423
http://dx.doi.org/10.1038/s43856-023-00340-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447459/
https://www.ncbi.nlm.nih.gov/pubmed/37612423
http://dx.doi.org/10.1038/s43856-023-00340-7

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