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Data-mining unveils structure–property–activity correlation of viral infectivity enhancing self-assembling peptides

Gene therapy via retroviral vectors holds great promise for treating a variety of serious diseases. It requires the use of additives to boost infectivity. Amyloid-like peptide nanofibers (PNFs) were shown to efficiently enhance retroviral gene transfer. However, the underlying mode of action of thes...

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Detalles Bibliográficos
Autores principales: Kaygisiz, Kübra, Rauch-Wirth, Lena, Dutta, Arghya, Yu, Xiaoqing, Nagata, Yuki, Bereau, Tristan, Münch, Jan, Synatschke, Christopher V., Weil, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447463/
https://www.ncbi.nlm.nih.gov/pubmed/37612273
http://dx.doi.org/10.1038/s41467-023-40663-6