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A randomized phase 2 study on demeclocycline in patients with mild-to-moderate COVID-19

Tetracyclines exhibit anti-viral, anti-inflammatory, and immunomodulatory activities via various mechanisms. The present study investigated the efficacy and safety of demeclocycline in patients hospitalized with mild-to-moderate COVID-19 via an open-label, multicenter, parallel-group, randomized con...

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Detalles Bibliográficos
Autores principales: Iwahori, Kota, Nii, Takuro, Yamaguchi, Norihiko, Kawasaki, Takahiro, Okamura, Satomi, Hashimoto, Kazuki, Matsuki, Takanori, Tsujino, Kazuyuki, Miki, Keisuke, Osa, Akio, Goya, Sho, Abe, Kinya, Mori, Masahide, Takeda, Yoshito, Yamada, Tomomi, Kida, Hiroshi, Kumanogoh, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447520/
https://www.ncbi.nlm.nih.gov/pubmed/37612352
http://dx.doi.org/10.1038/s41598-023-41051-2