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Haspin balances the ratio of asymmetric cell division through Wnt5a and regulates cell fate decisions in mouse embryonic stem cells

Many different types of stem cells utilize asymmetric cell division (ACD) to produce two daughter cells with distinct fates. Haspin-catalyzed phosphorylation of histone H3 at Thr3 (H3T3ph) plays important roles during mitosis, including ACD in stem cells. However, whether and how Haspin functions in...

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Detalles Bibliográficos
Autores principales: Gao, Yingying, Ma, Bin, Li, Yifan, Wu, Xiangyu, Zhao, Shifeng, Guo, Huiping, Wang, Yiwei, Sun, Lihua, Xie, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447528/
https://www.ncbi.nlm.nih.gov/pubmed/37612272
http://dx.doi.org/10.1038/s41420-023-01604-w