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A glutamatergic DRN–VTA pathway modulates neuropathic pain and comorbid anhedonia-like behavior in mice

Chronic pain causes both physical suffering and comorbid mental symptoms such as anhedonia. However, the neural circuits and molecular mechanisms underlying these maladaptive behaviors remain elusive. Here using a mouse model, we report a pathway from vesicular glutamate transporter 3 neurons in the...

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Detalles Bibliográficos
Autores principales: Wang, Xin-Yue, Jia, Wen-Bin, Xu, Xiang, Chen, Rui, Wang, Liang-Biao, Su, Xiao-Jing, Xu, Peng-Fei, Liu, Xiao-Qing, Wen, Jie, Song, Xiao-Yuan, Liu, Yuan-Yuan, Zhang, Zhi, Liu, Xin-Feng, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447530/
https://www.ncbi.nlm.nih.gov/pubmed/37612268
http://dx.doi.org/10.1038/s41467-023-40860-3