Trim33 masks a non-transcriptional function of E2f4 in replication fork progression

Replicative stress promotes genomic instability and tumorigenesis but also presents an effective therapeutic endpoint, rationalizing detailed analysis of pathways that control DNA replication. We show here that the transcription factor E2f4 recruits the DNA helicase Recql to facilitate progression o...

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Detalles Bibliográficos
Autores principales: Rousseau, Vanessa, Einig, Elias, Jin, Chao, Horn, Julia, Riebold, Mathias, Poth, Tanja, Jarboui, Mohamed-Ali, Flentje, Michael, Popov, Nikita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447549/
https://www.ncbi.nlm.nih.gov/pubmed/37612308
http://dx.doi.org/10.1038/s41467-023-40847-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447549/
https://www.ncbi.nlm.nih.gov/pubmed/37612308
http://dx.doi.org/10.1038/s41467-023-40847-0

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