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Trim33 masks a non-transcriptional function of E2f4 in replication fork progression
Replicative stress promotes genomic instability and tumorigenesis but also presents an effective therapeutic endpoint, rationalizing detailed analysis of pathways that control DNA replication. We show here that the transcription factor E2f4 recruits the DNA helicase Recql to facilitate progression o...
Autores principales: | Rousseau, Vanessa, Einig, Elias, Jin, Chao, Horn, Julia, Riebold, Mathias, Poth, Tanja, Jarboui, Mohamed-Ali, Flentje, Michael, Popov, Nikita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447549/ https://www.ncbi.nlm.nih.gov/pubmed/37612308 http://dx.doi.org/10.1038/s41467-023-40847-0 |
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