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An integrated proteome and transcriptome of B cell maturation defines poised activation states of transitional and mature B cells

During B cell maturation, transitional and mature B cells acquire cell-intrinsic features that determine their ability to exit quiescence and mount effective immune responses. Here we use label-free proteomics to quantify the proteome of B cell subsets from the mouse spleen and map the differential...

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Detalles Bibliográficos
Autores principales: Salerno, Fiamma, Howden, Andrew J. M., Matheson, Louise S., Gizlenci, Özge, Screen, Michael, Lingel, Holger, Brunner-Weinzierl, Monika C., Turner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447577/
https://www.ncbi.nlm.nih.gov/pubmed/37612319
http://dx.doi.org/10.1038/s41467-023-40621-2