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C1GalT1 expression reciprocally controls tumour cell-cell and tumour-macrophage interactions mediated by galectin-3 and MGL with double impact on cancer development and progression

Although most cell membrane proteins are modified by glycosylation, our understanding of the role and actions of protein glycosylation is still very limited. β1,3galactosyltransferase (C1GalT1) is a key glycosyltransferase that controls the biosynthesis of the Core 1 structure of O-linked mucin type...

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Detalles Bibliográficos
Autores principales: Wan, Yangu, Adair, Kareena, Herrmann, Anne, Shan, Xindi, Xia, Lijun, Duckworth, Carrie A., Yu, Lu-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447578/
https://www.ncbi.nlm.nih.gov/pubmed/37612278
http://dx.doi.org/10.1038/s41419-023-06082-7