Single-dose pharmacokinetics and lung function of nebulized niclosamide ethanolamine in sheep

PURPOSE: Niclosamide is approved as an oral anthelminthic, but its low oral bioavailability hinders its medical use requiring high drug exposure outside the gastrointestinal tract. An optimized solution of niclosamide for nebulization and intranasal administration using the ethanolamine salt has bee...

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Detalles Bibliográficos
Autores principales: Weiss, Anne, Bischof, Robert J, Landersdorfer, Cornelia B, Nguyen, Tri-Hung, Davies, Andrew, Ibrahim, Jibriil, Wynne, Paul, Wright, Phillip, Ditzinger, Günter, Montgomery, A Bruce, Meeusen, Els, McIntosh, Michelle P, Sommer, Morten OA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447587/
https://www.ncbi.nlm.nih.gov/pubmed/37498498
http://dx.doi.org/10.1007/s11095-023-03559-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10447587/
https://www.ncbi.nlm.nih.gov/pubmed/37498498
http://dx.doi.org/10.1007/s11095-023-03559-0

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