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A programmable pAgo nuclease with RNA target-cleavage specificity from the mesophilic bacterium Verrucomicrobia : A pAgo with RNA target cleavage specificity

Argonaute (Ago) proteins are conserved programmable nucleases present in eukaryotes and prokaryotes and provide defense against mobile genetic elements. Almost all characterized pAgos prefer to cleave DNA targets. Here, we describe a novel pAgo from Verrucomicrobia bacterium (VbAgo) that can specifi...

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Detalles Bibliográficos
Autores principales: Liu, Qi, Chen, Wanping, Zhang, Yue, Hu, Fengyang, Jiang, Xiaoman, Wang, Fei, Liu, Yang, Ma, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448046/
https://www.ncbi.nlm.nih.gov/pubmed/37431184
http://dx.doi.org/10.3724/abbs.2023110