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Sex-biased genome-editing effects of CRISPR-Cas9 across cancer cells dependent on p53 status
The CRISPR-Cas9 system has emerged as the dominant technology for gene editing and clinical applications. One major concern is its off-target effect after the introduction of exogenous CRISPR-Cas9 into cells. Several previous studies have investigated either Cas9 alone or CRISPR-Cas9 interactions wi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448110/ https://www.ncbi.nlm.nih.gov/pubmed/37636042 http://dx.doi.org/10.1016/j.isci.2023.107529 |