A unique poly(A) tail profile uncovers the stability and translational activation of TOP transcripts during neuronal differentiation

Cell differentiation is associated with global changes in translational activity. Here, we characterize how mRNA poly(A) tail processing supports this dynamic. We observe that decreased translation during neuronal differentiation of P19 cells correlates with the downregulation of 5′-terminal oligopy...

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Detalles Bibliográficos
Autores principales: Baptissart, Marine, Papas, Brian N., Chi, Ru-pin Alicia, Li, Yin, Lee, Dongwon, Puviindran, Bhairavy, Morgan, Marcos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448114/
https://www.ncbi.nlm.nih.gov/pubmed/37636056
http://dx.doi.org/10.1016/j.isci.2023.107511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448114/
https://www.ncbi.nlm.nih.gov/pubmed/37636056
http://dx.doi.org/10.1016/j.isci.2023.107511

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