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adducin 1 is essential for the survival of erythroid precursors via regulating p53 transcription in zebrafish

Adducin 1 (Add1) is known as a membrane cytoskeletal protein, but its nuclear function remains unclear. In this study, we generated add1-deficient zebrafish to investigate its role in hematopoiesis. Lack of add1 impaired both primitive and definitive hematopoiesis, preventing healthy erythrocyte dev...

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Detalles Bibliográficos
Autores principales: Yang, Shuyan, Cao, Shanhu, Xu, Xuebing, Li, Quan, Li, Jianting, Guo, Jin, Wang, Fang, Bao, Yihua, Jiang, Zean, Zhang, Ting, Wang, Li, Sun, Shaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448115/
https://www.ncbi.nlm.nih.gov/pubmed/37636049
http://dx.doi.org/10.1016/j.isci.2023.107516