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adducin 1 is essential for the survival of erythroid precursors via regulating p53 transcription in zebrafish
Adducin 1 (Add1) is known as a membrane cytoskeletal protein, but its nuclear function remains unclear. In this study, we generated add1-deficient zebrafish to investigate its role in hematopoiesis. Lack of add1 impaired both primitive and definitive hematopoiesis, preventing healthy erythrocyte dev...
Autores principales: | Yang, Shuyan, Cao, Shanhu, Xu, Xuebing, Li, Quan, Li, Jianting, Guo, Jin, Wang, Fang, Bao, Yihua, Jiang, Zean, Zhang, Ting, Wang, Li, Sun, Shaoguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448115/ https://www.ncbi.nlm.nih.gov/pubmed/37636049 http://dx.doi.org/10.1016/j.isci.2023.107516 |
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