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Photocycle alteration and increased enzymatic activity in genetically modified photoactivated adenylate cyclase OaPAC

Photoactivated adenylate cyclases (PACs) are light activated enzymes that combine blue light sensing capacity with the ability to convert ATP to cAMP and pyrophosphate (PPi) in a light-dependent manner. In most of the known PACs blue light regulation is provided by a blue light sensing domain using...

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Detalles Bibliográficos
Autores principales: Raics, Katalin, Pirisi, Katalin, Zhuang, Bo, Fekete, Zsuzsanna, Kis-Bicskei, Nikolett, Pecsi, Ildiko, Ujfalusi, Kinga Pozsonyi, Telek, Elek, Li, Yin, Collado, Jinnette Tolentino, Tonge, Peter J., Meech, Stephen R., Vos, Marten H., Bodis, Emoke, Lukacs, Andras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448171/
https://www.ncbi.nlm.nih.gov/pubmed/37468104
http://dx.doi.org/10.1016/j.jbc.2023.105056