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Deletion of the CYP2D6 gene as a likely explanation for the serious side effects of the antipsychotic drug pimozide: a case report

CYP2D6 analysis prior to the prescription of pimozide is required above a certain dose by the Food and Drug Administration in order to detect individuals with the poor metabolizer status. This precautionary measure aims to prevent the occurrence of serious adverse drug reactions. This study presents...

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Detalles Bibliográficos
Autores principales: Facal, Fernando, Portela, Begoña, Gil-Rodríguez, Almudena, Barros, Francisco, Maroñas, Olalla, Carracedo, Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448185/
https://www.ncbi.nlm.nih.gov/pubmed/37637419
http://dx.doi.org/10.3389/fphar.2023.1237446