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New supramolecules of bis(acylhydrazones)-linked bisphenol sulfide for Alzheimer's: targeting cholinesterases by in vitro and in silico approaches

In current research, two functional components, i.e., hydrazone and bisphenol sulfide were combined to get useful supramolecules in medicinal chemistry. Herein 25 new 4,4′-thiodiphenol bis-acylhydrazones were synthesized in good to excellent yields. Initially ethyl-2-chloroacetate was reacted with 4...

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Detalles Bibliográficos
Autores principales: Ibrahim, Muhammad, Ali, Mumtaz, Halim, Sobia Ahsan, Latif, Abdul, Ahmad, Manzoor, Ali, Sajid, SameeUllah, Khan, Ajmal, Rebierio, Alany Ingrido, Uddin, Jalal, Al-Harrasi, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448230/
https://www.ncbi.nlm.nih.gov/pubmed/37636505
http://dx.doi.org/10.1039/d3ra03908k