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MATN3 delivered by exosome from synovial mesenchymal stem cells relieves knee osteoarthritis: Evidence from in vitro and in vivo studies

BACKGROUND: Synovial mesenchymal stem cell (SMSC) exerts chondroprotective effects in osteoarthritis (OA) clinical models. However, the regulatory potentials of SMSC-derived exosomes (SMSC-Exo) in OA still need to be discovered, which attracted our attention. METHODS: The destabilization of the medi...

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Detalles Bibliográficos
Autores principales: Long, Long, Zou, Guoyou, Cheng, Yi, Li, Feng, Wu, Hao, Shen, Yixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448336/
https://www.ncbi.nlm.nih.gov/pubmed/37635810
http://dx.doi.org/10.1016/j.jot.2023.06.003