Easy, Robust, and Repeatable Online Acid Cleavage of Proteins in Mobile Phase for Fast Quantitative LC-MS Bottom-Up Protein Analysis—Application for Ricin Detection

[Image: see text] Sample preparation involving the cleavage of proteins into peptides is the first critical step for successful bottom-up proteomics and protein analyses. Time- and labor-intensiveness are among the bottlenecks of the commonly used methods for protein sample preparation. Here, we rep...

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Detalles Bibliográficos
Autores principales: Naplekov, Denis K., Jadeja, Siddharth, Fučíková, Alena Myslivcová, Švec, František, Sklenářová, Hana, Lenčo, Juraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448442/
https://www.ncbi.nlm.nih.gov/pubmed/37565982
http://dx.doi.org/10.1021/acs.analchem.3c01772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448442/
https://www.ncbi.nlm.nih.gov/pubmed/37565982
http://dx.doi.org/10.1021/acs.analchem.3c01772

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