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The SSBP3 co-regulator is required for glucose homeostasis, pancreatic islet architecture, and beta-cell identity
OBJECTIVE: Transcriptional complex activity drives the development and function of pancreatic islet cells to allow for proper glucose regulation. Prior studies from our lab and others highlighted that the LIM-homeodomain transcription factor (TF), Islet-1 (Isl1), and its interacting co-regulator, Ld...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10448474/ https://www.ncbi.nlm.nih.gov/pubmed/37536498 http://dx.doi.org/10.1016/j.molmet.2023.101785 |